Comparing Tools for Fitting Mutational Signatures: The Results of Our Work
2024-3-19 05:24:22 Author: hackernoon.com(查看原文) 阅读量:8 收藏
2024-3-19 05:24:22 Author: hackernoon.com(查看原文) 阅读量:8 收藏
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Mutational signatures based on single base substitutions are defined using the mutated base and its two neighboring bases. The total number of different “neighborhoods” (nucleotide contexts) to which each individual SBS can be attributed is 96 (6 different possible substitutions times four possible 5′ neighbors times four possible 3′ neighbors).
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